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Genomics Research and Cancer

Apr 04, 2017

Genomics Research and Cancer

Genomes are sets of genes present in an organism that are responsible for every anatomical and physiological traits the organism possesses and exhibits. Every cell in the human body has a genome including the cancer cells. By studying the genes of the cancer cells, its genomes can be determined by a method known as cancer genome sequencing. This method can reveal mutations and abnormalities in the genes of the cancer cells which make them develop and spread in the body. Once properly understood, the study of cancer genomes can help us understand cancer better thereby giving us a better opportunity if treating and it.

A person gets cancer, any type of cancer, when genes of a particular cell mutate causing them to multiply rapidly and spread to the body thereby causing hindrance in the normal functioning of the biological system.  Once the mutations in the genes are known and understood, it becomes easier for researchers to come up with specific therapies and treatments that would focus on these genetic changes to treat the cancer. In 2011, a specific mutation in the BRAF gene was discovered in patients suffering from melanoma, a type of skin cancer. Researchers came up with a drug that specifically targets this mutation and this drug was then approved by FDA for use on patients with melanoma. This is how important genomics research is when it comes to cancer care.

Presently, several research projects are in process to detect the genetic mutations and genomic changes that occur in a number of cancers to help develop specific treatments for them. These research projects have revealed changes which are constant in several types of cancer, and development of a single targeted treatment would be beneficial in treating them all.

Many alterations to the genome have been detected, but some of them are yet to be determined to do their lack of detailed characteristics. But the rapid advances in technology and also the data that has been achieved through recent studies should help in determining the mutations in genes and the DNA of cancer cells of many types of cancer. Whatever knowledge is gained through genomic research would be used to develop specific and special treatments and drugs for different type of cancer and would also be helpful in the diagnosis of the same.

Disclaimer: The information given in this write-up is purely for educating the reader. It is not meant to be a substitute for any advice from a medical expert.Genomes are sets of genes present in an organism that are responsible for every anatomical and physiological traits the organism possesses and exhibits. Every cell in the human body has a genome including the cancer cells. By studying the genes of the cancer cells, its genomes can be determined by a method known as cancer genome sequencing. This method can reveal mutations and abnormalities in the genes of the cancer cells which make them develop and spread in the body. Once properly understood, the study of cancer genomes can help us understand cancer better thereby giving us a better opportunity if treating and it.

A person gets cancer, any type of cancer, when genes of a particular cell mutate causing them to multiply rapidly and spread to the body thereby causing hindrance in the normal functioning of the biological system.  Once the mutations in the genes are known and understood, it becomes easier for researchers to come up with specific therapies and treatments that would focus on these genetic changes to treat the cancer. In 2011, a specific mutation in the BRAF gene was discovered in patients suffering from melanoma, a type of skin cancer. Researchers came up with a drug that specifically targets this mutation and this drug was then approved by FDA for use on patients with melanoma. This is how important genomics research is when it comes to cancer care.

Presently, several research projects are in process to detect the genetic mutations and genomic changes that occur in a number of cancers to help develop specific treatments for them. These research projects have revealed changes which are constant in several types of cancer, and development of a single targeted treatment would be beneficial in treating them all.

Many alterations to the genome have been detected, but some of them are yet to be determined to do their lack of detailed characteristics. But the rapid advances in technology and also the data that has been achieved through recent studies should help in determining the mutations in genes and the DNA of cancer cells of many types of cancer. Whatever knowledge is gained through genomic research would be used to develop specific and special treatments and drugs for different type of cancer and would also be helpful in the diagnosis of the same.

Disclaimer: The information given in this write-up is purely for educating the reader. It is not meant to be a substitute for any advice from a medical expert.

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