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Human Papilloma Virus – Types and Diseases associated

Mar 31, 2017

Human Papilloma Virus – Types and Diseases associated

Human papilloma virus can be classified into 5 genera: Alphapapillomavirus, Betapapillomavirus, Gammapapillomavirus, Mupapillomavirus and Nupapillomavirus. Complete sequencing has been done for more than 170 human papillomavirus types.  At least 200 more viruses have been identified and awaiting classification.

HPV type

Disease

1, 2, 4, 63

Plantar warts : benign epithelial tumors on the sole or toes of foot.

2, 7, 22

Common warts : small, hard, symptomless, rough growth on skin whose color is similar to skin.

3, 10, 8

Flat warts or Verruca plana, which is a flat-surfaced, slightly raised well-demarcated, reddish-brown or flesh-colored papule of 2 to 5 mm diameter. 

6, 11, 42, 44

Anogenital warts which occur singly but more often in clusters in the external or internal surfaces of anal or genital area like or labia majora of vagina, scrotum, penile shaft etc. anal or genital area.

6, 16, 18, 31, 53, 58

Anal dysplasia: it is a pre-cancerous condition in the lining of the anal canal

Highest risk: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 Probably high-risk: 26, 53, 66, 68, 73, 82

Genital cancers

5, 8

Epidermodysplasia verruciformis (tree man illness)-EV is an extremely rare autosomal recessive hereditary skin disorder characterized by growth of scaly macules and papules, on hands and feet. 

13, 32

Focal epithelial hyperplasia of mouth (Heck's disease) is an asymptomatic, benign neoplastic disease characterized by multiple white and pink papules in oral cavity.

6, 7, 11, 16, 32

Mouth papillomas

16

oropharyngeal squamous cell carcinomas

60

Verrucous cyst  (Cystic papillomas)

6, 11

Laryngeal papillomatosis (recurrent respiratory papillomatosis or glottal papillomatosis) 

 

Latest Notable Cases

In January 2016, a 25-year-old man Abul Bajandar from Bangladesh was diagnosed with Epidermodysplasia verruciformis. In March 2007, a Romanian man named Ion Toader was diagnosed with EV. He underwent surgery in 2013 and became almost disease free. In November 2007, 34-year-old Indonesian man named Dede Koswara was reported to have been suffering from the illness. Despite surgeries, he died in January 2016, owing to several complications.

Disclaimer: The information given in this write-up is purely for educating the reader. It is not meant to be a substitute for any advice from a medical expert.

 

 

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