Apr 11, 2017
Cancer is a significant obstruction and a great challenge in the world of medicine and several studies have been undertaken so as to determine new methods for cure and treatment of this deadly disease. A few medical researchers aim solely on producing drugs which will assist patients deal with the callous effects of chemotherapy, whilst others focus on natural treatment.
A certain clinical trial discovered that it is quite safe to frequently instill lung and brain cancer patients with 800 to 1000 times more of the everyday amount of vitamin C as an impending approach to enhance the result of standard treatments meant for cancer. On 30th March 2017, a particular work exhibited in cancer cell, the researchers from University of Iowa have demonstrated trail through which changed iron metabolism in cancer cells, and not normal cells, result in escalated sensitivity to cancer cell death as an outcome of elevated dose of vitamin C.
According to reports a research doctor working on the trial accidentally found a cure for sepsis and the solution is vitamin C. The latest research from the University of Iowa set out the results of their clinical trials and the outcome supports the vitamin C claim which was found earlier.
A research team from the Holden Comprehensive Cancer Center at the University of Iowa probed whether how is cancer cells affected by vitamin C, particularly non-small cell lung cancer (NSCLC) and brain cancer glioblastoma multiforme (GBM). The trials concluded that when mixed with other radiation treatments and chemotherapy, the anti-cancer agent is great affected in a safe and efficient manner by regular doses of vitamin C.
The UI assistant professor and the study author of radiation oncology Bryan Allen said, “These two diseases really haven’t had a significant improvement in outcomes for two or three decades.”
How does it function?
Too much of anything might prove bad; however, however, the human body is exceptional when it comes to fighting cancer. This is due to the intravenous dosage of vitamin C which is rendered actually 1000 times higher than the concentration of a healthy person has in their blood stream, that is nearly 70 micromolar. The aim is to have 20,000 micromolar of vitamin C in a cancer patient’s blood.
The escalated concentration of the vitamin C mucks up the metabolism of cancer cell by interrupting the levels of iron in the cells. Sequentially, this makes the iron react to the vitamin C and develop free radicals which could become weak and eliminate the DNA. This is when the radiation and the chemotherapy kill the cancer cells.
The trials depicted no extreme side effects to the patients who were apart of the trial and there was on the whole an escalation in the rate of survival.
Why is this whole process safe?
High levels of vitamin C do no harm to the normal cells. The research team found that the tumor tissue’s unusually large levels of redox active iron molecules counter with Vitamin C to result in hydrogen peroxide and free radicals extracted from hydrogen peroxide. Selective damage to the cancer cells are caused by these free radicals that lead to improved cancer cell death, at the same time sensitize chemotherapy and radiation in cancer cells.
Apr 11, 2017
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